Computed Tomography Findings of Diffuse Intracranial Calcifications in A Patient with Primary Hypoparathyroidism

Author(s): Ruhaid Khurram, Rahul Khamar and Srikanth Mandumula

Primary hypoparathyroidism is a rare endocrine condition characterised by an abnormally low level of parathyroid hormone (PTH) which has significant effects on calcium metabolism, homeostasis and can have a wide range of clinical manifestations. We report a case of a 43-year-old female who was referred to our emergency department following a witnessed generalised tonic-clonic seizure lasting seven minutes. Blood tests and investigations confirmed a diagnosis of primary hypoparathyroidism. Computed tomography (CT) imaging of the brain revealed rare findings of diffuse bilateral intracranial calcifications affecting the cerebellum, brainstem, basal ganglia, internal capsule and numerous other cortical areas.