Deleterious Impact of Non-Diabetic Cataract Surgery on the Values of Biomarkers of Oxidative Stress and Metabolic Syndrome in Kinshasa
Author(s): Christian Mwembo Nkolomonyi, Moise Mvitu Muaka, Edith Mboyo Efeko, Ndimbani Malosa Franck, Nganga Nkanga Mireille Solange, Héritier Mawalala Malengele, Christian Kisoka Lusunsi, Benjamin Longo-Mbenza.
Study Background and Purpose: Cataract is considered a structural marker of systemic metabolic disorders. Its association with metabolic syndrome (MS) and oxidative stress has only been well established in diabetic patients. The objective of the present study was to evaluate the impact of non-diabetic cataract surgery on biomarkers of SM and oxidative stress according to the pre-post operative phases.
Material and Methods: This was a mixed study, a consecutive series combining an intervention (quasi-experimental study before and after cataract surgery), a documentary study (patient file), a comparative and evaluative approach involving 163 patients over the age of 40, during a period from September 1 to December 31, 2022 at the MASINA Ophthalmological Center. Nominal variables were presented as frequencies, while quantitative variables as means ± SD. Pearson's Chi-Square test and Yates' Chi-Square test were used to compare the proportions between two groups. The threshold for statistical significance was set at any value of P