Intestinal Tumor Mast Cells in a Pomeranian Dog - Case Report

Author(s): Alfredo Klesse Neto and Paolo Ruggero Errante

Mast cells are hematopoietic cells distributed in connective tissue, primarily in organs that have primary contact with external antigens. Mast cell proliferative disorders include mastocytoma, which is most commonly seen in dogs in the cutaneous or subcutaneous tissue. Canine intestinal mastocytoma is a rare malignant neoplasm in small animal veterinary practice, and its diagnosis involves a combination of history, clinical examination, imaging, cytology, histopathology, and immunohistochemistry. The recommended treatment involves surgical resection of the tumor mass through enterectomy with enteroanastomosis with wide margins. The prognosis for animals affected by the disease is considered poor regardless of the degree of histological dedifferentiation. In this case report, we describe a seven-year-old male Pomeranian dog diagnosed with intestinal mastocytoma after histopathology and immunohistochemistry for KIT.