Advancements in biomaterials and implant design has created a lasting impact on orthopedic surgery. Changes such as implant longevity, biocompatibility, and patient satisfaction have been attained with the use of new biomaterials. Contemporary implants have been able to balance mechanical strength, corrosion resistance, wear characteristics, and biological integration all while decreasing complications including infection and periprosthetic fractures. Metallic biomaterials include titanium alloys, cobalt-chromium alloys, and stainless steel. These materials excel in durability and have favorable strength-to-weight ratios. Although, there are challenges when introducing new biomaterials in orthopedic surgery. Stress shielding and wear-induced osteolysis and stress shielding. This has prompted improvements to implant geometry, surface modifications, and material compositions. Polymeric components such as ultra-high molecular weight polyethylene has undergone significant refinement over the last several years leading to a reduction in oxidative degradation and debris formation. Newer technologic advancements in porous coatings, bioactive surface treatments, additive manufacturing, and patient-specific implant design have shown to further enhance osseointegration and biomechanics compatibility. The interplay between material science, biomechanics, and host biology is essential for ideal implant optimization and reducing the number of revisions. Continued research integrating materials engineering and clinical outcomes will drive the next generation of durable, biologically integrated orthopedic implants.