Background: Paraquat poisoning is a major cause of pesticide-related morbidity and poor clinical outcomes in low- and middle-income countries. Data from Bangladesh is still scarce. This study was conducted to evaluate clinical features, renal involvement, and short-term outcomes of paraquat poisoning and compare findings with existing literature.

Methods: This prospective observational study was conducted from January to July 2023 at Mymensingh Medical College Hospital. Fifty-four patients with confirmed paraquat ingestion were enrolled. Clinical features, laboratory findings, renal outcomes, and five-week outcomes were analyzed.

Findings: The mean age was 21.98 ± 8.85 years, with male predominance (61.1%). Most patients presented within 24 hours (77.8%). Common features included nausea (96.3%), altered consciousness (88.9%). vomiting (79.6%) and oral ulceration (75.9%), Renal failure developed in 72.2% of patients, and 35.2% required hemodialysis. The overall mortality rate was 57.4%.

Conclusion: Owing to its continued availability and severe outcomes, paraquat poisoning represents a significant public health problem, highlighting the dire need for preventive strategies, regulatory control, and standardized management guidelines.